Vitamin E

Vitamin E consists of a group of fat-soluble antioxidants including 4 tocopherols and 4 tocotrienols, the most active isomer of which is alpha-tocopherol. Vitamin E’s most important function in the body is as an antioxidant. Vitamin E scavenges free radicals involved in lipid oxidation that can damage fatty acids in neurons [Tardy, 2020].

Vitamin E supplementation can help improve menstrual-related migraine attakcs [Ziaei, 2009], reduce depression [Manosso, 2022], and decrease the risk of dementia [Masaki, 2000; Zandi, 2004].

References

Manosso LM, Camargo A, Dafre AL, Rodriguez ALS. Vitamin E for the management of major depressive disorder: possible role of the anti-inflammatory and antioxidant systems. Nutr Neurosci 2022;25:1310-24

Masaki KH, et al. Association of vitamin E and C supplement use with cognitive function and dementia in elderly men. Neurology 2000;54:1265–1272

Tardy AL, Pouteau E, Marquez D, et al. Vitamins and minarels for energy, fatigue, and cognition: a narrative review of the biochemical and clinical evidence. Nutrients 2020;12:228

Ziaei S, Kazemnejad A, Sedighi A. The effect of vitamin E on the treatment of menstrual migraine. Med. Sci. Monit. Int. Med. J. Exp. Clin. Res. 2009;15:CR16–CR19

Zandi PP, et al. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. Arch. Neurol. 2004;61:82–88